A simple, painless, non-invasive urine test that can be done at home could diagnose prostate cancer early with extremely high accuracy, even greater than the blood test currently used. This opens up the possibility of identifying cancer in its early stages, improving the outcome of treatments for what is one of the most common causes of death in men.
The result is due to the combination of artificial intelligence and genetic analysis, which has allowed the identification of new indicators of the disease in the study published in the journal "Cancer Research" by the research group led by the Swedish Karolinska Institute.
By analyzing gene activity in thousands of cells from prostate tumors, the researchers were able to create digital models of this tumor, which were then studied with artificial intelligence algorithms to identify proteins that could be used as biomarkers.
The molecular traces found in this way were searched for in samples taken from tumors, in the blood and in the urine of almost two thousand patients. Some of the biomarkers present in urine have proven to be the most reliable, not only in detecting the presence of cancer, but also its severity.
"There are many advantages to measuring biomarkers in urine," says Mikael Benson, study coordinator. "It is a non-invasive and painless test, and the sample can be analyzed using routine methods in clinical laboratories. New and more accurate biomarkers could lead to earlier diagnosis and better prognosis for men with prostate cancer. They could also reduce the number of unnecessary prostate biopsies in healthy men," the researcher adds. (A2 Televizion)